{"id":527452,"date":"2025-03-11T14:24:12","date_gmt":"2025-03-11T14:24:12","guid":{"rendered":"https:\/\/veteo.eu\/?page_id=527452"},"modified":"2026-04-29T11:50:53","modified_gmt":"2026-04-29T11:50:53","slug":"endocrinology","status":"publish","type":"page","link":"https:\/\/veteo.eu\/en\/services\/endocrinology\/","title":{"rendered":"Endocrinology"},"content":{"rendered":"

[vc_row css=”.vc_custom_1764154073255{margin-bottom: 50px !important;}” el_class=”en-st-pt”][vc_column][vc_row_inner equal_height=”yes” content_placement=”middle”][vc_column_inner width=”1\/2″][vc_column_text css_animation=”left-to-right” css=””]<\/p>\n

Thyroid gland<\/p>\n

Hyperthyroidism<\/h2>\n

It is the most common endocrine disease in cats, and its treatment requires repeated follow-up examinations.<\/p>\n

The most common treatment for feline hyperthyroidism is pharmacotherapy with methimazole (thiamazole). However, its use requires regular laboratory monitoring, and the recommended tests include:[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/2″][vc_single_image image=”524773″ img_size=”full” alignment=”right” css_animation=”right-to-left” css=””][\/vc_column_inner][\/vc_row_inner][vc_row_inner equal_height=”yes” content_placement=”top” gap=”10″][vc_column_inner width=”1\/3″ css=”.vc_custom_1635666472031{margin-bottom: 0px !important;padding-top: 50px !important;padding-right: 50px !important;padding-bottom: 50px !important;padding-left: 50px !important;background-color: #f2f2f2 !important;border-radius: 25px !important;}”][vc_column_text css=”.vc_custom_1764153900635{margin-bottom: 0px !important;}”]<\/p>\n

Total T4<\/sub><\/h3>\n

Allows assessment of treatment effectiveness and safety, and helps adjust the medication dosage.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/3″ css=”.vc_custom_1635666598858{margin-bottom: 0px !important;padding-top: 50px !important;padding-right: 50px !important;padding-bottom: 50px !important;padding-left: 50px !important;background-color: #f9f9f9 !important;border-radius: 25px !important;}”][vc_column_text css=”.vc_custom_1764153958904{margin-bottom: 0px !important;}”]<\/p>\n

Complete Blood Count<\/h3>\n

Allows for early detection of dangerous hematologic disorders that may occur as potential side effects of treatment (immune-mediated hemolytic anemia, thrombocytopenia, agranulocytosis).[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/3″ css=”.vc_custom_1635666565007{margin-bottom: 0px !important;padding-top: 50px !important;padding-right: 50px !important;padding-bottom: 50px !important;padding-left: 50px !important;background-color: #f2f2f2 !important;border-radius: 25px !important;}”][vc_column_text css=”.vc_custom_1764153981639{margin-bottom: 0px !important;}”]<\/p>\n

ALT, AST, ALP<\/h3>\n

They help to indirectly assess the effectiveness of therapy (liver enzyme activity is elevated in most cats with hyperthyroidism and gradually decreases after treatment begins) and to detect concurrent liver disease or the rare occurrence of drug-induced hepatopathy following methimazole administration.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner equal_height=”yes” content_placement=”top” gap=”10″][vc_column_inner width=”1\/3″ css=”.vc_custom_1635666598858{margin-bottom: 0px !important;padding-top: 50px !important;padding-right: 50px !important;padding-bottom: 50px !important;padding-left: 50px !important;background-color: #f9f9f9 !important;border-radius: 25px !important;}”][vc_column_text css=”.vc_custom_1764154000915{margin-bottom: 0px !important;}”]<\/p>\n

Creatinine, Urea, Phosphorus<\/h3>\n

Allow early detection of renal insufficiency \u201cmasked\u201d by hyperthyroidism or monitoring its severity throughout the course of treatment.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/3″ css=”.vc_custom_1635666472031{margin-bottom: 0px !important;padding-top: 50px !important;padding-right: 50px !important;padding-bottom: 50px !important;padding-left: 50px !important;background-color: #f2f2f2 !important;border-radius: 25px !important;}”][vc_column_text css=”.vc_custom_1764154034410{margin-bottom: 0px !important;}”]<\/p>\n

TSH<\/h3>\n

It makes it possible to identify iatrogenic hypothyroidism and false euthyroidism in patients with decreased total T4<\/sub> concentrations.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row css=”.vc_custom_1764154250812{margin-bottom: 50px !important;padding-top: 50px !important;}”][vc_column][vc_row_inner equal_height=”yes” content_placement=”middle”][vc_column_inner width=”1\/2″][vc_single_image image=”524781″ img_size=”full” css_animation=”left-to-right” css=””][\/vc_column_inner][vc_column_inner width=”1\/2″][vc_column_text css_animation=”right-to-left” css=””]<\/p>\n

Adrenal Cortex<\/p>\n

Hyperfunction of the Adrenal Cortex<\/h2>\n

This is a commonly diagnosed endocrinopathy in older dogs. Its treatment requires regular laboratory testing.<\/p>\n

Trilostane (Vetoryl\u00ae, Dechra) is currently the only medication approved for the treatment of hyperadrenocorticism in dogs. Monitoring a patient treated with trilostane involves careful clinical assessment and regular laboratory evaluations, including the following recommended tests:[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner equal_height=”yes” content_placement=”top” gap=”10″][vc_column_inner width=”1\/3″ css=”.vc_custom_1635666472031{margin-bottom: 0px !important;padding-top: 50px !important;padding-right: 50px !important;padding-bottom: 50px !important;padding-left: 50px !important;background-color: #f2f2f2 !important;border-radius: 25px !important;}”][vc_column_text css=”.vc_custom_1764154443487{margin-bottom: 0px !important;}”]<\/p>\n

ACTH Stimulation Test
\n(3\u20134 hours after trilostane administration)<\/h3>\n

The test of choice for monitoring trilostane therapy. It allows assessment of the degree of corticosteroid suppression in the adrenal cortex and helps guide adjustments to the medication dosage.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/3″ css=”.vc_custom_1635666598858{margin-bottom: 0px !important;padding-top: 50px !important;padding-right: 50px !important;padding-bottom: 50px !important;padding-left: 50px !important;background-color: #f9f9f9 !important;border-radius: 25px !important;}”][vc_column_text css=”.vc_custom_1764154473620{margin-bottom: 0px !important;}”]<\/p>\n

Cortisol (before trilostane administration)<\/h3>\n

An alternative to the ACTH stimulation test, recommended by other scientific studies.*[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/3″ css=”.vc_custom_1635666565007{margin-bottom: 0px !important;padding-top: 50px !important;padding-right: 50px !important;padding-bottom: 50px !important;padding-left: 50px !important;background-color: #f2f2f2 !important;border-radius: 25px !important;}”][vc_column_text css=”.vc_custom_1764154510508{margin-bottom: 0px !important;}”]<\/p>\n

Na and K<\/h3>\n

Helps assess the degree of suppression of mineralocorticoid activity in the adrenal cortex.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner equal_height=”yes” content_placement=”top” gap=”10″][vc_column_inner width=”1\/3″ css=”.vc_custom_1635666598858{margin-bottom: 0px !important;padding-top: 50px !important;padding-right: 50px !important;padding-bottom: 50px !important;padding-left: 50px !important;background-color: #f9f9f9 !important;border-radius: 25px !important;}”][vc_column_text css=”.vc_custom_1764154608454{margin-bottom: 0px !important;}”]<\/p>\n

ALT, ALP<\/h3>\n

Enable assessment of decreasing alkaline phosphatase activity and improvement of steroid-induced hepatopathy during treatment, as well as detection of concurrent primary liver disease.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/3″ css=”.vc_custom_1635666472031{margin-bottom: 0px !important;padding-top: 50px !important;padding-right: 50px !important;padding-bottom: 50px !important;padding-left: 50px !important;background-color: #f2f2f2 !important;border-radius: 25px !important;}”][vc_column_text css=”.vc_custom_1764154624009{margin-bottom: 0px !important;}”]<\/p>\n

Creatinine, Urea, Phosphorus<\/h3>\n

Allow detection of renal insufficiency, which frequently accompanies Cushing\u2019s syndrome in older dogs or may develop during iatrogenic adrenal cortex hypofunction.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/3″ css=”.vc_custom_1635666565007{margin-bottom: 0px !important;padding-top: 50px !important;padding-right: 50px !important;padding-bottom: 50px !important;padding-left: 50px !important;background-color: #f2f2f2 !important;border-radius: 25px !important;}”][vc_column_text css=”.vc_custom_1764154664070{margin-bottom: 0px !important;}”]<\/p>\n

Total Protein, Albumin, Globulins<\/h3>\n

Help monitor hydration status and detect protein metabolism disorders or inflammatory conditions that may occur concurrently with Cushing\u2019s syndrome.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner equal_height=”yes” content_placement=”top” gap=”10″][vc_column_inner width=”1\/3″ css=”.vc_custom_1635666472031{margin-bottom: 0px !important;padding-top: 50px !important;padding-right: 50px !important;padding-bottom: 50px !important;padding-left: 50px !important;background-color: #f2f2f2 !important;border-radius: 25px !important;}”][vc_column_text css=”.vc_custom_1764154681157{margin-bottom: 0px !important;}”]<\/p>\n

Cholesterol<\/h3>\n

Enables assessment of the degree of improvement in lipid metabolism during trilostane therapy.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/3″ css=”.vc_custom_1635666598858{margin-bottom: 0px !important;padding-top: 50px !important;padding-right: 50px !important;padding-bottom: 50px !important;padding-left: 50px !important;background-color: #f9f9f9 !important;border-radius: 25px !important;}”][vc_column_text css=”.vc_custom_1764154707233{margin-bottom: 0px !important;}”]<\/p>\n

Glucose<\/h3>\n

Allows detection of diabetes, which often occurs concurrently with Cushing\u2019s syndrome in older dogs.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_column_text css=”.vc_custom_1764943041366{margin-top: 60px !important;}”]<\/p>\n

*\u00a0Macfarlane<\/b>\u00a0L, Parkin T, Ramsey I.\u00a0Pre-trilostane and three-hour post-trilostane cortisol to monitor trilostane therapy in dogs.Vet Rec.<\/i>\u00a02016;179:597.<\/a>
\n<\/b>*<\/span> Ramsey<\/b>\u00a0I, MacFarlane L, Fracassi F, Galac S, Reusch C.\u00a0The repeatability of various cortisol measurements in clinically stable dogs with hyperadrenocorticism being treated with trilostane.<\/i>\u00a0Conference paper. ECVIM Congress 2016.<\/a><\/p>\n

[\/vc_column_text][\/vc_column][\/vc_row][vc_row css_animation=”top-to-bottom” el_id=”algorytmy” css=”.vc_custom_1741785790232{padding-top: 80px !important;padding-bottom: 80px !important;}”][vc_column][vc_column_text css=””]<\/p>\n

Algorithms<\/h2>\n

Algorithm for monitoring hyperthyroidism therapy using the therapeutic profile (methimazole)<\/h3>\n

[\/vc_column_text][vc_single_image image=”527708″ img_size=”full” alignment=”center” css=””][\/vc_column][\/vc_row][vc_row css_animation=”top-to-bottom” css=”.vc_custom_1741785780729{padding-top: 80px !important;padding-bottom: 80px !important;}”][vc_column][vc_column_text css=””]<\/p>\n

Algorithm for monitoring hyperadrenocorticism (HAC) therapy using the therapeutic profile (trilostane\u2013cortisol)<\/h3>\n

[\/vc_column_text][vc_single_image image=”527712″ img_size=”full” alignment=”center” css=””][\/vc_column][\/vc_row][vc_row css_animation=”top-to-bottom” css=”.vc_custom_1741785802655{padding-top: 80px !important;padding-bottom: 80px !important;}”][vc_column][vc_column_text css=””]<\/p>\n

Algorithm for monitoring hyperadrenocorticism (HAC) therapy using the therapeutic profile (trilostane\u2013ACTH stimulation)<\/h3>\n

[\/vc_column_text][vc_single_image image=”527715″ img_size=”full” alignment=”center” css=””][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” equal_height=”yes” content_placement=”middle” css=”.vc_custom_1635676283661{padding-top: 80px !important;padding-bottom: 80px !important;background-color: #f3f3f3 !important;}” el_id=”profily”][vc_column css=”.vc_custom_1635440227432{padding-right: 30px !important;}”][vc_column_text css=””]<\/p>\n

Profiles<\/h2>\n

Hyperthyroidism<\/h3>\n

[\/vc_column_text][vc_row_inner][vc_column_inner width=”1\/2″][vc_column_text css=”” el_class=”profilee”]<\/p>\n

Therapeutic profile (methimazole) \u2013 basic<\/h4>\n

T4 + complete blood count + ALT, AST, ALP, creatinine, urea, phosphorus[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/2″][vc_column_text css=”” el_class=”profilee”]<\/p>\n

Therapeutic profile (methimazole) \u2013 extended<\/h4>\n

therapeutic profile (methimazole) \u2013 basic + TSH[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_column_text css=”.vc_custom_1764162146009{padding-top: 90px !important;}”]<\/p>\n

Hyperfunction of the adrenal cortex<\/h3>\n

[\/vc_column_text][vc_row_inner][vc_column_inner width=”1\/2″][vc_column_text css=”” el_class=”profilee”]<\/p>\n

Therapeutic profile (trilostane \u2013 ACTH stimulation)
\u2013 basic<\/h4>\n

2\u00d7 cortisol + Na, K[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/2″][vc_column_text css=”” el_class=”profilee”]<\/p>\n

Therapeutic profile (trilostane \u2013 cortisol) \u2013 basic<\/h4>\n

cortisol + Na, K[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_row_inner][vc_column_inner width=”1\/2″][vc_column_text css=”” el_class=”profilee”]<\/p>\n

Therapeutic profile (trilostane \u2013 ACTH stimulation)<\/h4>\n

2\u00d7 cortisol + Na, K + ALP, ALT, creatinine, urea, phosphorus, total protein, albumin, globulins, cholesterol, glucose[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/2″][vc_column_text css=”” el_class=”profilee”]<\/p>\n

Therapeutic profile (trilostane \u2013 cortisol)<\/h4>\n

cortisol + Na, K + ALP, ALT, creatinine, urea, phosphorus, total protein, albumin, globulins, cholesterol, glucose[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row][vc_column css=”.vc_custom_1763043051266{padding-top: 100px !important;padding-bottom: 0px !important;}” offset=”vc_hidden-sm vc_hidden-xs”][vc_column_text css=”.vc_custom_1764161985805{margin-bottom: 40px !important;}” el_class=”accent-text-color”]<\/p>\n

Veterinary Diagnostics<\/strong><\/h2>\n

made simple<\/strong><\/h2>\n

[\/vc_column_text][vc_single_image image=”478648″ img_size=”130×120″ alignment=”center” css_animation=”top-to-bottom” css=”.vc_custom_1763043206895{margin-bottom: 0px !important;border-top-width: 20px !important;}”][\/vc_column][\/vc_row][vc_row][vc_column css=”.vc_custom_1763043108982{padding-top: 75px !important;padding-bottom: 0px !important;}” offset=”vc_hidden-lg vc_hidden-md”][vc_column_text css=”” el_class=”accent-text-color”]<\/p>\n

Veterinary Diagnostics<\/strong><\/h2>\n

made simple<\/strong><\/h2>\n

[\/vc_column_text][vc_single_image image=”478648″ img_size=”130×120″ alignment=”center” css=”.vc_custom_1734266787739{margin-bottom: 0px !important;border-top-width: 20px !important;}”][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row css=”.vc_custom_1764154073255{margin-bottom: 50px !important;}” el_class=”en-st-pt”][vc_column][vc_row_inner equal_height=”yes” content_placement=”middle”][vc_column_inner width=”1\/2″][vc_column_text css_animation=”left-to-right” css=””] Thyroid gland Hyperthyroidism It is the most common endocrine disease in cats, and its treatment requires repeated follow-up examinations. The most common treatment for feline hyperthyroidism is pharmacotherapy with methimazole (thiamazole). However, its use requires regular laboratory monitoring, and the recommended tests include:[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/2″][vc_single_image image=”524773″…<\/p>\n","protected":false},"author":5,"featured_media":523868,"parent":527411,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-527452","page","type-page","status-publish","has-post-thumbnail","hentry","description-off"],"acf":[],"yoast_head":"\nEndocrinology - Veteo.eu - Modern veterinary laboratories<\/title>\n<meta name=\"description\" content=\"Endocrine diagnostics for pets, including monitoring of hyperthyroidism in cats and adrenal disorders in dogs.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/veteo.eu\/en\/services\/endocrinology\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Endocrinology - 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