{"id":527339,"date":"2025-02-28T07:59:34","date_gmt":"2025-02-28T07:59:34","guid":{"rendered":"https:\/\/veteo.eu\/our-diagnostic-services\/allergy-diagnostics\/allergiediagnostik-technologien\/"},"modified":"2026-04-29T08:02:08","modified_gmt":"2026-04-29T08:02:08","slug":"technologies","status":"publish","type":"page","link":"https:\/\/veteo.eu\/en\/services\/allergy-diagnosis\/technologies\/","title":{"rendered":"Allergy diagnosis – Technologies"},"content":{"rendered":"

[vc_row el_class=”en-st-pt”][vc_column css=”.vc_custom_1764246651578{padding-top: 0px !important;}”][vc_single_image image=”524666″ img_size=”full” css=””][vc_column_text css=””]<\/p>\n

The company Nextmune has launched a new-generation allergy test called PAX\u00ae (Pet Allergy Xplorer)<\/span>. It is a molecular and fully quantitative analysis. By using both allergen extracts and molecular components simultaneously, the test enables a more precise identification of the key allergy-triggering substances.<\/h3>\n

The PAX\u00ae test is now also available for cats and horses![\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=””]<\/p>\n

In cooperation with Nextmune, we offer you a test specifically developed for animals, based on the assessment of IgE antibodies against individual molecular components within an allergen. This molecular method is successfully used in human medicine and is now also available in veterinary diagnostics.<\/h3>\n

Conventional allergy tests performed in veterinary laboratories worldwide use allergen extracts. These extracts contain both proteins responsible for triggering an allergic reaction and others that have no effect. For example, the house dust mite extract \u2014 one of the most common allergens in dogs and cats \u2014 is obtained by grinding the mites, adding solvents, and purifying the peptides. The resulting mixture contains more than 10,000 proteins, but only about 40 of them trigger an immunological reaction. This means that the extract contains only a small proportion of truly relevant peptides for the allergy. Isolating the clinically significant protein components from this mixture and analyzing the specific IgE antibodies directed against them significantly increases the precision of the test result.[\/vc_column_text][vc_single_image image=”524662″ img_size=”full” alignment=”center” css=””][vc_empty_space][\/vc_column][\/vc_row][vc_row][vc_column width=”2\/3″][vc_column_text css=””]<\/p>\n

CCD molecules<\/span><\/strong><\/h2>\n

Thanks to the introduction of the PAX\u00ae method, it is now possible to apply CCD-blocking \u2014 used to eliminate false-positive results \u2014 also in horses! Until now, this technology was available only for allergy testing in dogs and cats.<\/p>\n

What are CCD molecules?<\/strong><\/p>\n

CCD (Cross-reactive Carbohydrate Determinants) are structural components of many allergenic proteins, especially plant-derived allergens such as pollen. During an allergic reaction, IgE antibodies are produced against both the carbohydrate chains and the protein portion of the allergens. Studies show that IgE directed against CCD particles occur in about 30% of tested animals but have no clinical relevance<\/strong>.<\/p>\n

Eliminating IgE that bind specifically to CCD particles improves the correlation between in-vitro test results and intradermal tests.<\/p>\n

[\/vc_column_text][\/vc_column][vc_column width=”1\/3″][vc_single_image image=”527346″ img_size=”full” css=””][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/4″][vc_column_text css=””]Waiting time for results:<\/strong> 7\u201314 days
Test material:<\/strong> 0.5 ml serum[\/vc_column_text][\/vc_column][vc_column width=”3\/4″][vc_column_text css=””]NOTE: The immune system reaches full maturity after the first year of life. For this reason, it is not recommended to perform an allergy test before the animal is eighteen months old. <\/span><\/strong>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column]

<\/div>[\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=””]<\/p>\n

Advantages of PAX\u00ae <\/span><\/strong>– Allergy Tests:<\/span><\/strong><\/h2>\n
    \n
  • \n

    Analysis of allergen extracts and molecular components<\/strong> \u2013 The results provide more detailed information compared to previous serological and intradermal tests.<\/p>\n<\/li>\n

  • \n

    More effective CCD-molecule blocking<\/strong> \u2013 Only allergens that are truly involved in the allergic disease are detected.<\/p>\n<\/li>\n

  • \n

    Dual CCD-blocking control<\/strong> \u2013 After verifying the first blocking step, the process is repeated if necessary.<\/p>\n<\/li>\n

  • \n

    Identification of cross-reactivities<\/strong> \u2013 The use of isolated allergenic proteins allows identification of the primary source of the allergy.<\/p>\n<\/li>\n

  • \n

    More precise allergen identification<\/strong> \u2013 Enables a more targeted and effective hyposensitisation therapy.<\/p>\n<\/li>\n

  • \n

    Fully quantitative test<\/strong> \u2013 Results show the concentration of IgE in the sample in ng\/ml.<\/p>\n<\/li>\n

  • \n

    Fully automated test procedure<\/strong> \u2013 Reduces time-consuming manual steps.<\/p>\n<\/li>\n

  • \n

    Only 0.5 ml of serum required<\/strong> \u2013 The previous generation of Nextmune+ allergy tests required 1 ml of serum.<\/p>\n<\/li>\n<\/ul>\n

    [\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/4″][vc_column_text css=””]Waiting time for results:<\/strong> 7\u201314 days
    Test material:<\/strong> 0.5 ml serum[\/vc_column_text][\/vc_column][vc_column width=”3\/4″][vc_column_text css=””]NOTE: The immune system reaches full maturity after the first year of life. For this reason, it is not recommended to perform allergy testing in dogs and cats before twelve months of age, and in horses before eighteen months of age. <\/span><\/strong>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

    [vc_row el_class=”en-st-pt”][vc_column css=”.vc_custom_1764246651578{padding-top: 0px !important;}”][vc_single_image image=”524666″ img_size=”full” css=””][vc_column_text css=””] The company Nextmune has launched a new-generation allergy test called PAX\u00ae (Pet Allergy Xplorer). It is a molecular and fully quantitative analysis. By using both allergen extracts and molecular components simultaneously, the test enables a more precise identification of the key allergy-triggering substances. The PAX\u00ae test…<\/p>\n","protected":false},"author":5,"featured_media":523954,"parent":527089,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-527339","page","type-page","status-publish","has-post-thumbnail","hentry","description-off"],"acf":[],"yoast_head":"\nAllergy diagnosis - Technologies - Veteo.eu<\/title>\n<meta name=\"description\" content=\"PAX\u00ae molecular allergy testing \u2014 advanced, quantitative diagnostics that precisely identify key allergen components in animals.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/veteo.eu\/en\/services\/allergy-diagnosis\/technologies\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Allergy diagnosis - Technologies - Veteo.eu\" \/>\n<meta property=\"og:description\" content=\"PAX\u00ae molecular allergy testing \u2014 advanced, quantitative diagnostics that precisely identify key allergen components in animals.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/veteo.eu\/en\/services\/allergy-diagnosis\/technologies\/\" \/>\n<meta property=\"og:site_name\" content=\"veteo.eu - 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